CLENPIQ is ready for you to drink right from the bottle. With a SingleCare Clenpiq coupon, the retail price. bottle of Clenpiq. 1 out of 10 from a total of 253 ratings on Drugs. Drink an additional 5 cups (8 oz each) of water or clear liquids. Drink the entire contents. . It belongs to a group of medications called laxatives. each) of clear liquids or sports drink (except red or pink)An enzyme deficiency or rosacea may be behind the facial flush. bottle) of CLENPIQ. To use Clenpiq®: This medicine is available in a ready-to-drink bottle and is equal to one dose. Do not take other laxatives while taking CLENPIQ. Citric acid, magnesium oxide, and sodium picosulfate combination is used to cleanse the colon (bowel) in preparation for a procedure called colonoscopy. About CLENPIQ. LIQUIDS MUST NOT BE RED OR PURPLE. 6 hours prior to your scheduled procedure time drink the second bottle of CLENPIQ. Talk to your doctor or pharmacist if you have any. Do not take oral medications within one hour of starting CLENPIQ. Call Us Today at (907) 569-1333!Clenpiq oral solution, follow with (5)8oz clear liquid Detailed, step-by-step instructions continue on page 3 for patients with diabetes. Polyethylene glycol 3350 (PEG), an osmotic laxative that cleanses out your bowels by pulling water into your colon and causing you to have very watery diarrhea to get rid of the stools. , tricyclic antidepressants), patients withdrawing from alcohol or benzodiazepines, patients with known or suspected hyponatremia [see Adverse Reactions (6. com. Day of the exam. Drink 5 cups (8 ounces each) of clear liquid. m. After you finish Step 3 Follow with THREE (3) - 8oz glasses of clear liquid within the next 3 hours. Drink the entire first bottle. Administer tetracycline and fluoroquinolone antibiotics, iron, digoxin, chlorpromazine and penicillamine, at least 2 hours before and not less than 6 hours after administration of CLENPIQ to avoid chelation with magnesium. 1 . CLENPIQ is ready for you to drink right from the bottle. 985. g. Please for full Prescribing Information, including Medication Guide and Instructions for Use. Drink an 8 ounce glass of the mixture every 10 to 15 minutes until it is gone. com. Do not refrigerate or freeze CLENPIQ. // Drink another bottle of CLENPIQ® AND 4 cups (32 oz) or more of water. 5. anhydrous citric acid. 46% of reviewers reported a positive effect, while 31% reported a negative effect. NO SOLID FOOD UNTIL AFTER THE PROCEDURE. 8 oz LIQUIDS MUST NOT BE RED OR PURPLE. • Drink one (1) entire bottle of the CLENPIQ®. 5 Important Safety. drinks of clear liquid taken at your own pace within the next 5 hours. weight gain. CLENPIQ ® oral solution is indicated for cleansing of the colon as a preparation for colonoscopy in adults and pediatric patients ages 9 years and older. , tricyclic antidepressants), patients withdrawing from alcohol or benzodiazepines, patients with known or suspected hyponatremia [see Adverse. No Alcohol Procedure Day . This means that you are allowed to drink liquids like water or broth and eat plain jello or frozen juice bars. • Consume only clear fluids (no solid food) from the start of CLENPIQ treatment until after the colonoscopy. NO ALCOHOL o The correct timing of this dose is essential to an effective preparation. Prescription only. Clenpiq. Drink first container of Clenpiq 2. It is generally taken as two doses in preparation for a colonoscopy. • Do not take other laxatives while taking CLENPIQ. o Follow Clenpiq by drinking a minimum of four 8 ounce glasses of clear liquids. 2 out of 10 from a total of 76 ratings on Drugs. lean protein. Clenpiq and Suprep are both medications used to cleanse the bowel before a colonoscopy. Some side effects may occur that usually do not need medical attention. 5 hrs. PURCHASE CLENPIQ BOWEL PREP KIT (with a prescription sent directly to your pharmacy). To prevent becoming dehydrated, drink as much clear liquid as you can. Two separate doses of CLENPIQ are required for complete colonoscopy. Alcohol is not allowed as part of the clear liquid diet. o eat or drink anything colored red or purple. Step 3: Be sure to drink the entire contents of the bottle. This was horrible. Please ignore the instructions on the back of the Plenvu box which states you can take all of the prep the night before the procedure. CLENPIQ is ready for you to drink right from the bottle. You cannot have any solid foods, milk or alcohol while taking Clenpiq. Offer good only in the USA at participating retail pharmacies. Colonoscopy 2-Day, CLENPIQ -Continued • Day before procedure o BEGIN CLEAR LIQUID DIET. Continuing thirst. (2. Drug Interactions. • Do not drink alcohol. cup) for drinking 8 oz. There is 1 alcohol/food interaction with Clenpiq (citric acid/magnesium oxide/sodium picosulfate). Hookey L, et al. DO NOT CONSUME ANY ALCOHOL, JUICE PULP, MILK, CREAM, SOY OR NON-DAIRY CREAMER, OR. About CLENPIQ CLENPIQ is a ready-to-drink cranberry-flavored,. Side Effects. Which is really a relief because I have a family history of malignant colon cancer in my family. It does not need to be mixed or diluted. 4 oz. m. CLENPIQ can reduce the absorption of co-administered drugs. o. Drink first container of Clenpiq 2. View detailed information regarding this drug interaction. CLENPIQ (sodium picosulfate, magnesium oxide, and anhydrous citric acid) oral solution is a stimulant and osmotic laxative that is provided as a cranberry-flavored, colorless to slightly yellow, clear oral solution, and is supplied as two bottles in each carton. 64% of reviewers reported a positive effect, while 24% reported a negative effect. Drink 8 ounces of liquids every hour. Clenpiq is a medication used to help treat high levels of ammonia in the blood. 4. patients withdrawing from alcohol or benzodiazepines or patients with known or suspected hyponatremia. com. My experience / Clenpiq. It is a combination of sodium picosulfate, magnesium oxide, and anhydrous citric acid that works together to trigger bowel movements and empty the colon. Tell your doctor if you are pregnant or breastfeeding. Clenpiq has an average rating of 5. Use caution in patients who have conditions, or are taking concomitant medications that increase the risk for seizures, such as those taking medications that lower the seizure. Suprep Bowel Prep Kit has an average rating of 7. Alcohol/Food/Lifestyle Interactions: Oral medications may not be properly absorbed when they are taken within one hour before starting. Drink CLENPIQ right from the bottle 2. 4 oz bottle of CLENPIQ remaining. headache, severe or continuing. Mixing it with a flavored drink can enhance the taste of Clenpiq. DO NOT CONSUME ANY ALCOHOL, JUICE PULP, MILK, CREAM, SOY OR NON-DAIRY CREAMER, OR OTHER LIQUIDS YOU CANNOT SEE THROUGH. CÓMO TOMAR CLENPIQ: BEBER, HIDRATAR, REPETIR INDICACIONES CLENPIQ® es un medicamento de venta con receta usado por adultos y niños de 9 años de edad en adelante para limpiar el colon antes de una colonoscopia. – Take 1st and refrigerate prior to drinking. (True) Clenpiq and Suprep have the same active ingredients. CLENPIQ cleans your colon by causing you to have diarrhea. of clear liquids within 5 hours of completion of the Clenpiq solution. // As you finish your prep, your stools should be clear/yellow and watery in appearance. Had no results by the time my 2nd bottle was due at 9pm, just some belly rumblings. This medicine can cause severe dehydration, which can lead to a serious electrolyte imbalance, seizures, kidney failure, or abnormal heartbeats that can cause death. ensure adequate hydration and anTO OPEN THE CLENPIQ BOTTLE, BREAK THE SEAL FIRST, THEN TURN TO OPEN CAP 6:00pm First Dose: 1. 9pm – start 2nd dose • Follow steps 1 – 2 above. There are 649 drug interactions with Clenpiq (citric acid/magnesium oxide/sodium picosulfate). • Do not drink alcohol. You can visit this link to get a Clenpiq coupon that can save you 10%-75% off your medication at your local pharmacy. Drinking fluids following prep will help prevent dehydration See EMAIL for your BEGINNING TIME for the first drinking of prepHow PEG 3350/electrolytes bowel prep works. Some nonsteroidal anti-inflammatory drugs, such as celecoxib (Celebrex) The migraine medication sumatriptan (Imitrex) Certain "water pills" (diuretics), such as furosemide (Lasix) and. should be used within 24 hours. • Drink at least eight - 8oz glasses of clear liquid (64oz) during the day prior to starting your prep. DO NOT CONSUME ANY ALCOHOL, JUICE PULP, MILK, CREAM, SOY OR NON-DAIRY CREAMER, OR OTHER LIQUIDS YOU CANNOT SEE THROUGH. Administer. This medicine can cause severe dehydration, which can lead to a serious electrolyte imbalance, seizures, kidney failure, or abnormal heartbeats that can cause death. Videos. Do not drink milk, other dairy products, red/dark-colored liquids, or alcohol. Immediately follow with 40 ounces of water over the next hour. All Drugs; Human Drugs; Animal Drugs. m. Within the next two hours: Drink at least five 8-ounce glasses of clear liquids. CLENPIQ ANHYDROUS CITRIC ACID 12 g/160mL Ferring Pharmaceuticals Inc. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. NOTE: If you have Type 1 diabetes, please discuss an acceptable clear liquid diet with your Endocrinologist. Do not take oral medications within one hour of starting CLENPIQ. Started to work within an hour. Subject to eligibility and maximum benefit allowed. bottle of preparation solution. 47% of reviewers reported a positive effect, while 40% reported a negative effect. See the instructions for CLENPIQ is a prescription medicine that cleans your colon. It is a dual-acting, combination of sodium picosulfate, a stimulant laxative, and magnesium oxide and anhydrous citric acid, which forms magnesium citrate, an osmotic laxative indicated for cleansing of the colon as a preparation for colonoscopy in adults. Indication. It is designed to work quickly and effectively. Step 3: Be sure to drink the entire contents of the bottle. DO NOT refrigerate, freeze, or pour over ice. FIRST THING IN THE MORNING o NO SOLID FOOD. • Do not drink alcohol. All Drugs; Human Drugs; Animal Drugs. S. 2. Administer tetracycline and fluoroquinolone antibiotics, iron, digoxin, chlorpromazine and penicillamine, at least 2 hours before and not less than 6 hours after administration of CLENPIQ to avoid chelation with magnesium. eat solid foods, dairy such as milk, or alcohol while taking Clenpiq and until after your colonoscopy. 4 CONTRAINDICATIONS. , tricyclic antidepressants), patients withdrawing from alcohol or benzodiazepines, patients with known or suspected hyponatremia [see Adverse. Do not eat solid foods or drink alcohol, dairy, drinks, juices with pulp, soy milk, or any drinks, gelatin, or other liquids that are red or purple a day before your colonoscopy. 30055 Northwestern Hwy #250, Farmington Hills, Ml 48334 • 248. − Follow this dose by drinking at least five 8-ounce cups of clear liquids using the cup provided over the next few hours. Liquid diet all day then took first bottle of clenpiq at 4pm. It simply does not work well enough if taken the night before. 8 out of 10 from a total of 288 reviews on Drugs. 1. Use caution when prescribing CLENPIQ for patients with a history of seizures and in patients at risk of seizure, such as patients taking medications that lower the seizure threshold (e. If you are taking diabetic medication, cut your dose in half this day and do not take any diabetic medication day of procedure. Drink at least 8 glasses of water during the day to avoid dehydration. CLENPIQ is a prescription medicine that cleans your colon. Magnesium citrate, MiraLAX with Gatorade, MoviPrep, OsmoPrep, Prepopik/Clenpiq, and Suprep all had significantly higher prep tolerability compared with GoLYTELY (all P < 0. 1)What is CLENPIQ? (CLENPIQ) Sodium picosulfate/magnesium oxide/citric acid solution is used to clean out the intestines before surgery or certain procedures (such as colonoscopy, X-rays). trouble breathing. 5 g-10 mg/160 mL) will typically cost around $180 for 320 milliliters. DO NOT CONSUME ANY ALCOHOL, JUICE PULP, MILK, CREAM, SOY OR NON-DAIRY CREAMER, OR OTHER LIQUIDS YOU CANNOT SEE THROUGH. − Follow this dose by drinking at least five 8-ounce cups of clear liquids using the cup provided over the next few hours. dehydration from the bowel preparation. , tricyclic antidepressants), patients withdrawing from alcohol or benzodiazepines, patients with known or suspected hyponatremia [see Adverse Reactions (6. 28 ± 1. KEEP DRINKING CLEAR LIQUIDS UNTIL YOU GO TO SLEEP. You may have clear liquids all day. Clenpiq, Prepopik. org. alcohol for the rest of the day after your exam. Clenpiq Interactions. CLENPIQ is contraindicated in the following conditions: Patients with severe renal impairment (creatinine clearance less. , tricyclic antidepressants), patients withdrawing from alcohol or benzodiazepines, patients with known or suspected hyponatremia [see Adverse Reactions (6. Visicol. Do not eat solid food or dairy and do not drink anything colored red or purple. Do not refrigerate or freeze CLENPIQ. Indication. Si está tomando medicamentos (aparte de la. Administer tetracycline and fluoroquinolone antibiotics, iron, digoxin, chlorpromazine and penicillamine, at least 2 hours before and not less than 6 hours after administration of CLENPIQ to avoid chelation with magnesium. CLENPIQ limpia el colon produciéndole diarrea. CLENPIQ and other bowel preparations can cause serious side effects, including: x Serious loss of body fluid (dehydration) and changes in blood salts (electrolytes) in your blood. It does not need to be mixed or diluted. You may. Open one bottle of Clenpiq. It also helps the muscles in your intestines move stool. Does metronidazole topical interact with my other drugs? Enter other medications to view a detailed report. are withdrawing from drinking alcohol or from taking benzodiazepines. 5000 • 248. Don’t drink alcohol. 8 oz LIQUIDS MUST NOT BE RED OR PURPLE. weight gain. 1 . // Finish liquids 2 hours before your colonoscopy. 10PM: Drink second 160ml bottle of Clenpiq. CLENPIQ is a prescription medicine used by adults to clean the colon before a colonoscopy. g. 5 Important Safety. Clenpiq 10 mg-3. Use caution when prescribing CLENPIQ for patients with a history of seizures and in patients at risk of seizure, such as patients taking medications that lower the seizure threshold (e. Citric acid, magnesium oxide, and sodium picosulfate combination is used to cleanse the colon (bowel) in preparation for a procedure called colonoscopy. 5. ensure adequate hydration and anAbout CLENPIQ CLENPIQ is a ready-to-drink cranberry-flavored, dual-acting, combination of sodium picosulfate, a stimulant laxative, and magnesium oxide and anhydrous citric acid, which forms magnesium citrate, an osmotic laxative indicated for cleansing of the colon as a preparation for colonoscopy in adults. and 6 p. • Follow with at least three (3) 8 oz. CLENPIQ BOWEL PREP The following instructions are your physician’s specific instructions. Clenpiq for Bowel Preparation User Reviews (Page 2) Clenpiq has an average rating of 5. It’s important to be patient and give Clenpiq time to work. Administer tetracycline and fluoroquinolone antibiotics, iron, digoxin, chlorpromazine and penicillamine, at least 2 hours before and not less than 6 hours after administration of CLENPIQ to avoid chelation with magnesium. Clenpiq is a medication used to help treat high levels of ammonia in the blood. The first dose is usually taken the night before the colonoscopy and the second dose taken the. Clenpiq alcohol/food interactions. Continue to drink LOTS of clear liquids to prevent dehydration and headache until 10:00pm. drinks of clear liquid until midnight. It works by removing ammonia from the body, which can help reduce symptoms associated with high levels of ammonia. LAXATIVE BOWEL PREP START. Clenpiq. Title: Microsoft Word - CERTIFICATE FERRINGUS_14AUG2012 Author: drosner. drinks of clear liquid until midnight. Polyethylene glycol 3350 has an average rating of 7. 4pm: It should take you no more than 1 Take 4 tablespoons of Milk of Magnesia followed by 32 ounces of water over one hour. , tricyclic antidepressants), patients withdrawing from alcohol or benzodiazepines, patients with known or suspected hyponatremia [see Adverse. Prep outcome was excellent (like yours). Drink all of this medicine straight from the bottle. Shake well prior to drinking. 8 out of 10 from a total of 288 ratings on Drugs. There are 644 drugs known to interact with Clenpiq (citric acid/magnesium oxide/sodium picosulfate), along with 8 disease interactions, and 1 alcohol/food interaction. CLENPIQ is a ready-to-drink cranberry-flavored, dual-acting, combination of sodium picosulfate, a stimulant laxative, and magnesium oxide and anhydrous citric acid, which forms magnesium citrate, an osmotic laxative indicated for cleansing of the colon as a preparation for colonoscopy in adults. 4oz. Call your doctor at once if you have: no bowel movement within 2 hours after use; vomiting; dizziness, feeling like you might pass out;Consult your healthcare professional for medical advice on avoiding side effects of Clenpiq and other contraindications, warnings, and interactions that may apply to you, your health conditions, and your list of medications. NuLYTELY has an average rating of 5. Advertisement. To use the ColPrep Kit®: The ColPrep Kit® contains 2 bottles of ColPrep®, taken as a 2-day regimen (Split-dose method). Pour in the contents of 1 CLENPIQ packet and keep stirring for 2-3 minutes. CLENPIQ is a ready-to-drink cranberry-flavored, dual-acting, combination of sodium picosulfate, a stimulant laxative, and magnesium oxide and anhydrous citric acid, which forms magnesium citrate, an osmotic laxative indicated for cleansing of the colon as a preparation for colonoscopy in adults. Add water to the fill line and mix. Pricing. Geriatric useCLENPIQ prescription at the time the prescription is filled by the pharmacist and dispensed to the patient. b. It works by removing ammonia from the body, which can help reduce symptoms associated with high levels of ammonia. 985. Professional resources. You can also report other adverse reactions of Clenpiq to the FDA at 1-800-FDA-1088. Which prep is the one to have? Which is best to avoid? It's not so easy to tell. 47% of reviewers reported a positive experience, while 40% reported a negative experience. Please see chart above. As a guide, Clenpiq oral solution (12 g-3. Food and Drug Administration (FDA) after initiation of the study and was combined with the Prepopik® group. 6pm: Clenpiq Prep- (Part 1)• NO SOLID FOOD – NO ALCOHOL – NO RECREATIONAL DRUG USE • Follow the steps listed below: − At 5:00 P. with a small sip of water, bottle of Clenpiq solution. To prevent becoming dehydrated, drink as much clear liquid as you can before, during, and after drinking this medication. DISCONTINUE ALCOHOL until the day after your procedure. NO ALCOHOL o The correct timing of this dose is essential to an effective preparation. x 1 bottle of CLENPIQ equals 1 dose. But then you also have to follow the colonoscopy prep diet! Clear liquids aren’t exactly the most filling of foods. swelling of the eyelids, face, lips, ankles, hands, or feet. the evening before the procedure: — Drink the first 5. bottles) of Clenpiq prepand 1 (8oz. For those who find it difficult to complete a PEG bowel prep as instructed, a NaP formula can help encourage. To use Prepopik®: One dose of this medicine contains 2 packets of powder. Drank quickly 1st bottle Clenpiq at 3pm the day before. • Consume only clear fluids (no solid food) from the start of CLENPIQ treatment until after the colonoscopy. • Consume only clear liquids (no solid food) from the start of CLENPIQ treatment until after the colonoscopy. 5500 fax 11900 E. There are 408 drugs known to interact with Jardiance (empagliflozin), along with 3 disease interactions, and 1 alcohol/food interaction. 5-12 MG-GM-GM/160ML Solution. Efficacy and safety of a ready-to-drink bowel preparation for colonoscopy: a randomized, controlled, non-inferiority trial. ) of clear liquid every hour while awake. I’m here to help. CLENPIQ ® (sodium picosulfate, magnesium oxide, and anhydrous citric acid) Oral Solution (SPMC) was administered in a split-dose regimen against an oral powder (for reconstitution) (P/MC powder) and efficacy was evaluated using 2 different measurement scales. Updated on August 30, 2023. The sweetness of the juice helps to counterbalance the bitterness, making it much more palatable. (2. So trust the prep and the process lol. To use Clenpiq®: This medicine is available in a ready-to-drink bottle and is equal to one dose. 6pm: Begin Clenpiq Prep- Part 1 Step 1-Drink 1. It does not need to be mixed or diluted. No alcohol the day before or day of your procedure. One caveat: when Clenpiq begins to work you don’t want to dawdle getting to the bathroom :)". Drug Interactions. 5 Use caution when prescribing CLENPIQ for patients with a history of seizures and in patients at risk of seizure, such as patients taking medications that lower the seizure threshold (e. 9 p. 8 oz LIQUIDS MUST NOT BE RED OR PURPLE. Administer tetracycline and fluoroquinolone antibiotics, iron, digoxin, chlorpromazine and penicillamine, at least 2 hours before and not less than 6 hours after administration of CLENPIQ to avoid chelation with magnesium. Free coupon for. Use caution in patients who have conditions, or are taking concomitant medications that increase the risk for seizures, such as those taking medications that lower the seizure. Clenpiq has an average rating of 5. Each bottle of CLENPIQ contains 10 mg sodium picosulfate,. st. 8 out of 10 from a total of 288 ratings on Drugs. After taking Clenpiq, it typically takes about 30 minutes to 1 hour for the medication to start working. Alcohol/Food/Lifestyle Interactions: Oral medications may not be properly absorbed when they are taken within one hour before starting. 31. Each packet is mixed with cold water (5 ounces) for 2 to 3 minutes and taken at separate times. Drink all of this medicine straight from the bottle. Prepopik/Clenpiq, and SUPREP. — Then drink at least 40 oz. CLENPIQ and other bowel preparations can cause serious side effects, including: Serious loss of body fluid (dehydration) and changes in blood salts (electrolytes) in your blood. Complete steps 1-3 exactly as directed: Do NOT refrigerate bottles. I drank the 2nd bottle Clenpiq at 9pm. Colonoscopy CLENPIQ -Continued • Day before procedure o BEGIN CLEAR LIQUID DIET, FIRST THING IN THE MORNING o NO SOLID FOOD. CLENPIQ can reduce the absorption of co-administered drugs. Not fun to drink but I’ve had to drink bottles of barium for other tests before so this was nothing compared to that. It does NOT need to be mixed or diluted. CLENPIQ comes ready to drink and does not need to be mixed with anything else before you take your dose of medicine. 1)]. g. Clenpiq has an average rating of 5. Check off the cups below as you go! Start: Finish: Morning of your colonoscopy Drink the other bottle of CLENPIQ Drink CLENPIQ right from the bottle Then, keep hydrating Drink at least 3 cups (8 oz each) of clear liquid. • CLENPIQ and other bowel preparations can cause serious side effects, including serious loss of body fluid (dehydration) and changes in blood salts (electrolytes) in your blood. CLENPIQ is a combination of sodium picosulfate, a stimulant laxative, and magnesium oxide and anhydrous citric acid, which form magnesium citrate, an osmotic laxative, indicated for cleansing of the colon as a preparation for colonoscopy in adults and pediatric patients ages 9 years and older. It is a clear solution with possible presence of visible particles and it does not need to be diluted prior to administration. Clenpiq has an average rating of 5. Consume a bunch of laxatives and then poop pure liquid for hours. Drank the recommended water after. The selling, purchasing, trading, or counterfeiting of this card is prohibited by law. The recommended dosage in adults and pediatric patients 9 years of age and older is shown below. com. CLENPIQ right from the bottle. 5 grams of magnesium oxide, and 12 grams of anhydrous citric acid in 175 mL of colorless to slightly yellow, clear solution with. Clenpiq is an oral solution used to clean out your colon in preparation for a colonoscopy Although the treatment requires drinking a lot of fluids, it makes it easier for your healthcare provider to examine the inside of your colon during the procedure. So I'm going into to get a colonoscopy today. Clenpiq has an average rating of 5. Way less than the 1st dose, which kept me going for a few hours and then waking up in the night. It also helps the muscles in your intestines move stool. Indication. 791 Prematurity with major problems; 793 Full term neonate with major problems; 917 Poisoning and toxic effects of drugs with mcc; 918 Poisoning and toxic effects of drugs without mcc; Convert T50. I had a 12:15p checkin for a 1:15p appointment - I took my 2nd dose at 9am and stopped ingesting all liquids by 10:15a. PEG 3350/electrolytes bowel prep is a combination medication that contains:. CLENPIQ is indicated for cleansing of the colon as a preparation for colonoscopy in adults and pediatric patients 9 years of age and older. The chart shows what you can and cannot drink. The preps used for split dose preps are Plenvu, Osmoprep Tablets, Clenpiq, and Suprep. The preferred method is the "Split-Dose" method. (1)On the day before taking Clenpiq I made sure that I started to be well hydrated drinking lemonade chicken broth beef broth or any other liquid preparing my body for the 5 pm prep to start and then took a small dose of Clenpiq followed by 8 oz glass of liquid and continued until finished the 1 st bottle every half hr. Each packet is mixed with cold water (5 ounces) for 2 to 3 minutes and taken at separate times. m.